Role of interleukin-6 in the control of acute and chronic Giardia lamblia infections in mice.

نویسندگان

  • Ping Zhou
  • Erqiu Li
  • Nannan Zhu
  • Jason Robertson
  • Theodore Nash
  • Steven M Singer
چکیده

In this study, we investigated the role of interleukin-6 (IL-6) in Giardia lamblia infections in mice. Elevated IL-6 expression was found in wild-type mice 15 days postinfection. Furthermore, IL-6-deficient mice controlled infections only slowly although normal immunoglobulin A production was observed. Thus, IL-6 is necessary for early control of acute G. lamblia infections.

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عنوان ژورنال:
  • Infection and immunity

دوره 71 3  شماره 

صفحات  -

تاریخ انتشار 2003